Proven Benefits of CBD Oil for Psoriasis, Dosage & How to Use

CBD oil is a product obtained from the cannabis plant.

It is rich in a phytochemical called cannabinoid and thus it is called CBD oil. It lacks the psychoactive component of cannabis, THC and therefore it does not produce ‘high’ in the users.

It has been shown to have many therapeutic properties. It exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-seizure properties among others. Many scientific studies and account of personal use by patients report its effectiveness in many ailments.

What is Psoriasis?

Psoriasis is an autoimmune, chronic skin condition caused by the attack of the immune system on the body. It is characterized by inflammation, flaking of the skin.

The symptoms include red/white patches on the skin, flaking, itching, swelling, etc. The region of skin is called plaques and they occur commonly in knee, elbow, back, etc.

Psoriasis vulgaris is the most common form affecting 90% of the psoriasis patients. The causes include genetic reasons, drug-induced psoriasis, infections, chronic stress, lifestyle, etc.

Corticosteroids are applied topically and phototherapy is also commonly used for the treatment of psoriasis.

CBD Hemp Oil Benefits for Psoriasis

CBD oil can help alleviate psoriasis and its symptoms because of its anti-inflammatory, immunosuppressant, stress relieving, anti-infectious, analgesic, anti-oxidant properties among others.

These benefits are discussed in detail below –

1. CBD oil could Prevent Overgrowth of Skin Cells

In psoriasis patients, the skin is regenerated every 2-4 days instead of every 25-30 days as in the case of normal people.

This is due to the attack of the immune system on the skin cells. This overgrowth of skin cells is harmful as it causes scaling, itchiness, flaking, etc.

The overgrowth of skin can be prevented to alleviate symptoms of psoriasis including flaking, inflammation, etc.

A study tested CBD for inhibiting the growth of human keratinocyte. It was reported that CBD could effectively suppress the growth and proliferation of human keratinocyte in a dose-dependent manner.

Therefore it was suggested that CBD could be used for the treatment of psoriasis.


Psoriasis is characterized by overgrowth of the skin cells. CBD has been found to help suppresses the proliferation of the human skin cells.

Therefore it might be helpful in alleviating several symptoms of psoriasis including patching, swelling, flaking, etc.

2. CBD oil has Immuno-suppressant Properties

Psoriasis is an autoimmune disease in which the body initiates an attack on itself.

Down-regulation of the immune system is found to be useful in such cases in managing the symptoms. Suppressing the hyperactive immune system can help reduce flare-ups and discomfort.

CBD has been found to possess immune-suppressant properties. It has been shown that CBD induces death in human T lymphocyte cells.

It induces the CD4+ and CD8+ to undergo apoptosis (death). CBD induces death in these cells by caspase 3 and 8 activity.

3. CBD Oil has Anti-inflammatory Properties

Inflammation is common in many autoimmune diseases among other disorders.

Psoriasis is in fact classified as an immune-mediated inflammatory disease (IMID), which affects the skin.

The inflammation of skin and blood vessels in patients with psoriasis is common. This often results in swelling, pain, discomfort, etc.

The inflammation also causes other systemic disorders including co-morbidities such as cardiovascular disorders, obesity, diabetes, atherosclerosis, etc.

Tumor necrosis factor-alpha is unregulated in the patients and causes many metabolic abnormalities including insulin resistance, coronary events, etc.

Keeping inflammation at bay also keeps the risk of developing psoriatic arthritis low, which is important because nearly 15% patients end up developing psoriatic arthritis.

A study suggested that CBD could be used for the treatment of psoriasis due to its anti-inflammatory properties via the suppression of VEGF, MMPs among other pro-inflammatory mediators.

CBD has been proven to have significant anti-inflammatory properties. Studies have shown that use of CBD can reduce both chronic and acute intestinal inflammation.

CBD reduces the levels of tumor necrosis factor-alpha, which are found to be unregulated in psoriasis patients.

It also suppresses the NF-κB signalling pathway thus bringing down inflammation. CBD has been found to effective in the treatment of inflammatory arthritis such as rheumatoid arthritis. It also helps reduce the levels of IFN-γ in animal models of inflammatory arthritis.

Cannabidiol can also reduce the impact of inflammation on oxidative stress and thus reduce the risk of developing diseases driven by a combination of inflammation and oxidative stress.

CBD also has an impact on the immune system and immune cells and therefore alters the level of different cytokines in the body, which in turn results in an anti-inflammatory property.

Hemp seed oil (containing CBD) is rich in omega-3 PUFA, which has been found to help reduce inflammation. Effect of CBD on arachidonate metabolism also contributes to its anti-inflammatory properties.

A study showed that topical application of CBD could bring down the knee inflammation in animal models.

This could potentially help in preventing the onset with inflammatory psoriatic arthritis in the patients of psoriasis.


Inflammation can worsen psoriasis by inducing flare-ups and cause progression of other co-morbidities. CBD has been shown to be effective in alleviating inflammation and therefore it can be beneficial for the patients of psoriasis.

4. CBD Oil has Anti-infectious Properties

Infections can contribute to worsening of psoriasis. Bacterial and fungal infections are known to be associated with certain types of psoriasis.

Staphylococcus and Candida can contribute to flare-ups. Many medicines used for psoriasis also increase the risk of life-threatening infections.

Keeping infection is check can indirectly help prevent flare-ups and worsening of the disease.

CBD has some anti-infectious property associated with it. CBD has potent activity against antibiotic-resistant staphylococcus bacteria.

CBD suppresses the growth of many Gram-positive bacteria. It can help provide relief from itchy skin diseases.

Hemp seed oil makes the skin resistant to bacterial, viral and fungal infections. This can be attributed to the presence of Beta-sitosterol in hemp seed oil.


Infections caused by bacteria, fungi, virus, etc. have been found to have some association with psoriasis including flare-ups.

CBD oil has anti-microbial properties, which can help avoid infection related complications in psoriasis patients.

5. CBD oil helps Alleviate Stress

Stress can act as a trigger for psoriasis and cause it to flare up.

Discomfort associated with psoriasis also results in unwanted stress, anxiety, restlessness, fatigue, sleeplessness, etc.

Depression has been found to be 50% more prevalent in psoriasis patients.

Many experts have spoken about the importance of living a stress-free life in order to recover fast and prevent flare-ups.

Stress management is therefore important for the patients with psoriasis. Studies have highlighted the use of CBD oil for alleviating stress, anxiety, insomnia, etc.

Use of CBD in rat models for 21 days showed a significant reduction in stress. It also altered stress-induced behaviour in these rats.

CBD effectively reduces anxiety and allows the user to feel calmer even in situations of social anxiety and panic disorder.

CBD reduces the excess neuronal activity and thus brings calm to the user. CBD possesses significant anti-depressant property as well.

CBD oil is helpful in cases of insomnia as well. Pain and itchiness can result in sleepless nights in the patients, which is not good for the body and the mind.

Use of CBD allows the user to sleep better and experience quality sleep. 600mg of CBD has been shown to be effective in bringing down stress and anxiety.


Stress is a major trigger for psoriasis. It can not only cause psoriasis but also make it worse. Keeping stress under control is necessary.

CBD oil can help alleviate stress and anxiety. It also helps the user experience improved quality of sleep thus further reducing stress.

6. CBD oil is an Analgesic

Skin pain and discomfort is common in patients with psoriasis.

An exploratory study conducted with 139 patients with psoriasis reported that nearly 43% of patients suffered from pain and nearly 37% of them suffered from discomfort.

Unpleasant sensation, itchiness, hot/burning sensation were a few things reported by the patients.

Alleviation of pain and discomfort is necessary to ensure a better quality of life. CBD oil has been shown to help reduce pain and have an analgesic effect.

CBD increases the pain threshold and thus allows the patients to deal with pain. It alters the perception of pain.

Topical application of CBD has also found to be effective in reducing pain, swelling, etc. in animal models of arthritis.

Many studies have shown that CBD is effective in the management of difficult to treat pain as well. It has also been shown that CBD can be used for alleviating chronic pain associated with diseases like cancer and multiple sclerosis.


Pain has been found to be common in the patients of psoriasis. CBD oil can help ease the pain and provide some relief from the discomfort thus ensuring a better quality of life for the patients.

7. CBD Oil could help with Psoriasis Co-morbidities

Psoriasis is a systemic autoimmune disorder and it is associated with several comorbidities as many different organs and systems are affected by the disease.

Some common comorbidities include coronary heart diseases, psoriatic arthritis, depression, atherosclerosis, cancer, etc.

Preventing such comorbidities is important, as most of these are serious disorders, which can complicate the health condition of the patients.

CBD oil has been found to be effective in alleviating symptoms of many of these diseases. CBD oil is good for the heart and reduces the risk of coronary heart events. It also reduces plaque buildup in arteries (atherosclerosis).

CBD oil helps as an anti-depressant as well. It helps reduce the risk of cancer due to its anti-oxidant and anti-inflammatory properties. It could also help reduce metastasis of tumors.

CBD oil is a potent anti-inflammatory agent and it has been shown to be effective in alleviating inflammatory arthritis.

Therefore it could help prevent psoriatic arthritis or help alleviate the symptoms.


Psoriasis is associated with many comorbidities such as cancer, heart problems, depression, etc. CBD oil could help keep these at bay or help better manage these because of its diverse therapeutic properties as proven by many studies.

The dosage of CBD for Psoriasis

Studies often use 600mg of CBD for producing considerable plasma level of CBD. It is therefore advisable to consume nearly 600mg or more of CBD oil.

Patients should consume low dosage while starting out and gradually increase the dose in order to allow the body to get used to CBD.

Nearly 600mg of CBD is used for cases of anxiety and insomnia as well.

CBD oil is usually dropped under/over the tongue and then swirled in the mouth for a couple of minutes before swallowing.

Capsules can also be taken. The concentration of CBD in the preparation is key and only high purity CBD preparations should be used.

The oil can be mixed with creams and gels before application in some cases depending on the strength of the oil.

For topical use, the skin should be cleaned prior to application. Don’t come in contact with water after application of the oil on the skin.

Put a few drops on the skin and massage it lightly to allow penetration. Make sure the oil is safe for topical use by reading the label and consulting the seller if possible.

Precautions with CBD Oil

Few side effects commonly observed in users include low blood pressure, faintness, drowsiness, dry mouth, etc.

It should be avoided by the patients with Parkinson’s disease as it worsens the tremors.

Driving and other intensive activities should be avoided right after taking CBD.

Only high-quality CBD oil should be used even if it is expensive because cheap, adulterated ones can cause more harm than good.

It can also be safely consumed by children, as it does not cause alteration of senses. Pregnant and breastfeeding mothers should use it only on doctor’s advice.

There could be interactions with some anti-inflammatory drugs, steroids, blood pressure and diabetes medication, etc.

Therefore consultation with the doctor regarding the use of CBD oil is important to avoid any side effects.


Psoriasis is a common skin disease affecting many people around the globe.

It is a disease with no cure and therefore management of the disease and its symptoms is important.

There are many medicines available but they are not free from side effects. Therefore there is a need for a complementary regime with fewer side effects.

CBD oil can be used for managing psoriasis for several reasons. It helps reduce inflammation, alleviate stress, decrease pain and discomfort, etc. It can help maintain the overall improved quality of life in patients with psoriasis. It can be included with other medicines for the disease as long as they don’t show interactions.

CBD oil of high quality can be used by the patients after consultation with health care provider to ensure maximum benefits.